Can you back-up wii games with CloneCD and AnyDVD?

not sure, but even if it did, you will need some sort of boot method or modchip to play the backups. These have not yet been developed.

sorry to say slysoft package software for now works only with movie dvd and audio cd. maybe in the future they will make it into that part of the package but as for now the game company are constantly changes protections making it not worth in the end as it is for bypassing those on dvd and cd.