No not really. The latest patch for NWN seems to check software installed in your computer and if you have installed
CloneCD for instance the game will refuse to run. This doesn't look like PSX protection to me. However when you do not install the patch for NWN you can copy and play the game just fine! I've been playing from a back-up and it works fine as long as CloneCD's Hide CDR Media is enabled. NWN and WCIII just use an improved SecuRom protection which requires a reliable Subs reading (which is a problem for some Lite-on drives). Nothing special really. To my knowledge all three discs of NWN are protected but I've only back-upped disc 3 since this is the play disc and used the most.