I ran into this problem, and in my research, I've found a few things. Here is the one I'd suggest to try:
There are known problems causing this message, both resulting from third-party software using debugger-like approaches.
Nero 6 ultra edition - specifically Image Drive can cause this issue
Use the Nero “general clean utility” - available from the Nero website to remove the offending program and then the game works.
http://ww2.nero.com/enu/Clean_Tools.html